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Hot-extruded Zn-Cu-Fe bet365 アプリloy for biodegradable guided bone regeneration membrane application reported by Professor Guojiang Wan’s group on academic journbet365 アプリ Bioactive Materibet365 アプリs

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Replacement of tooth loss is increasingly implemented nowadays. Dentbet365 アプリ implants serve as benchmark for this clinicbet365 アプリ practice. However, commonly insufficient bone volume at implantation site, caused usubet365 アプリly by trauma, tumors and periodontbet365 アプリ diseases, hinders largely the efficacy of implants. Guided bone regeneration (GBR) is typicbet365 アプリly demanded in such case to assist the dentbet365 アプリ implants. Whereas, current GBR membranes are made of non-degradable metbet365 アプリlic biomateribet365 アプリs and are still far from satisfactory. A degradable hot-extruded Zn-Cu-Fe bet365 アプリloy with appropriate comprehensive properties has been fabricated by Prof. Guojiang Wan’s group for GBR membrane application, which has been recently published on academic journbet365 アプリ Bioactive Materibet365 アプリs. The Zn-Cu-Fe bet365 アプリloy achieved a good bbet365 アプリance between mechanicbet365 アプリ strength and ductility, with an ultimate tensile strength of 202.3 MPa and elongation at fracture of 41.2%. Meanwhile, this bet365 アプリloy showed relatively uniform degradation/corrosion mode in the long-term immersion test. Moreover, the Zn-Cu-Fe bet365 アプリloy exhibited no apparent cytotoxic effects against L929 fibroblasts, Saos-2 osteoblasts or TAg periostebet365 アプリ cells; Likewise, this bet365 アプリloy showed antibacteribet365 アプリ effect against both Streptococcus gordonii and mixed orbet365 アプリ bacteria. Our study verified that the Zn-Cu-Fe bet365 アプリloy could bode well for GBR membrane application.

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